interleukin 18 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T16570	Pralnacasan	VX-740,HMR 3480	Others
	Pralnacasan inhibits proinflammatory cytokines IL-18, IL-1β , and IFN-γ. Pralnacasan is an effective, non-peptide, and orally active interleukin-1β converting enzyme inhibitor (Ki: 1.4 nM). Pralnacasan has the potential ...
T10447	BAA473		Others
	BAA473 is a bile acid analog that is a potent activator of the pyrin inflammasome. BAA473 can induce secretion of interleukin-18 (IL-18) through activation of the inflammasome in both myeloid and intestinal epithelial c...
T62950	IRAK4-IN-18
	IRAK4-IN-18 is a potent inhibitor of interleukin 1 receptor-associated kinase 4 (IRAK4) (IC50: 15 nM). IRAK4-IN-18 inhibits LPS-induced IL23 production in THP and DC cells and blocks the development of arthritis in rats,...

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-02824	IL-18R alpha Protein, Rat, Recombinant (hFc)	Rat	HEK293 Cells
	IL-18R alpha Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 62.5kDa and the accession number is A0A8I6A1C2.
TMPY-03273	IL-18 Protein, Mouse, Recombinant	Mouse	E. coli
	IL-18 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18.2 kDa and the accession number is P70380-1.
TMPY-01928	IL-18 Protein, Rhesus, Recombinant (His)	Rhesus	E. coli
	IL-18 Protein, Rhesus, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.7 kDa and the accession number is Q9BGI5.
TMPY-03951	IL-18R alpha Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293 Cells
	IL-18R alpha Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.1 kDa and the accession number is F7H8F9.
TMPY-00846	IL-18BP Protein, Human, Recombinant (His)	Human	HEK293 Cells
	IL-18BP Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19 kDa and the accession number is A0A024R5G2.
TMPY-05492	IL-18BP Protein, Human, Recombinant (aa 1-192, hFc)	Human	HEK293 Cells
	IL-18BP Protein, Human, Recombinant (aa 1-192, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.4 kDa and the accession number is AAD17187.1.
TMPY-00277	IL-18 Protein, Human, Recombinant	Human	E. coli
	IL-18 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18.2 kDa and the accession number is Q14116-1.
TMPY-01376	IL-18R alpha Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	IL-18R alpha Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.8 kDa and the accession number is Q61098.
TMPY-03102	IL-18R beta/IL-18RAP Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293 Cells
	IL-18R beta/IL-18RAP Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.4 kDa and the accession number is XP_001108108.1.
TMPY-05782	IL-18R alpha Protein, Mouse, Recombinant (mFc)	Mouse	HEK293 Cells
	IL-18R alpha Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 61.74 kDa and the accession number is Q61098.
TMPY-01111	IL-18BP Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	IL-18BP Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.4 kDa and the accession number is Q9Z0M9.
TMPY-01219	IL-18R alpha Protein, Human, Recombinant (His)	Human	HEK293 Cells
	IL-18R alpha Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.2 kDa and the accession number is Q13478.
TMPY-05491	IL-18R alpha Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	IL-18R alpha Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 62.5 kDa and the accession number is Q13478.
TMPY-01446	IL-18R beta/IL-18RAP Protein, Human, Recombinant (His)	Human	HEK293 Cells
	IL-18R beta/IL-18RAP Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is O95256-1.
TMPY-00345	IL-18R alpha Protein, Canine, Recombinant (His)	Canine	HEK293 Cells
	IL-18R alpha Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.3 kDa.
TMPY-03911	IL-18R alpha Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	IL-18R alpha Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.9 kDa and the accession number is D3ZRM2.
TMPY-03901	IL-18R alpha Protein, Canine, Recombinant (hFc)	Canine	HEK293 Cells
	IL-18R alpha Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 62.9 kDa and the accession number is XP_854199.2.
TMPY-00509	IL-18R alpha Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	IL-18R alpha Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.6 kDa and the accession number is F7H8F9.
TMPY-00984	IL-18R alpha Protein, Mouse, Recombinant (His & hFc)	Mouse	HEK293 Cells
	IL-18R alpha Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 63.5 kDa and the accession number is Q61098.
TMPY-06750	IL-18R beta/IL-18RAP Protein, Rabbit, Recombinant (His)	Rabbit	HEK293 Cells
	IL-18R beta/IL-18RAP Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.22 kDa and the accession number is G1SQ92.
TMPY-03103	IL-18R beta/IL-18RAP Protein, Rhesus, Recombinant (His)	Rhesus	HEK293 Cells
	IL-18R beta/IL-18RAP Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.85 kDa and the accession number is XP_001108108.1.
TMPK-00492	IL-18BP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated	Cynomolgus	HEK293 Cells
	Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggestin...
TMPJ-00072	IL-18BPd Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Interleukin 18 binding protein (IL-18BP) is a physiological inhibitor that acts through binding to the receptor-binding site of IL-18. IL-18 stimulates INF-γ, which then stimulates 18BP production via NF-κB. The interact...
TMPY-06761	IL-18R beta/IL-18RAP Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	IL-18R beta/IL-18RAP Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.28 kDa and the accession number is A0A0G2K2K7.
TMPK-00491	IL-18BP Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggestin...
TMPY-03381	IL-18 Protein, Human, Recombinant (GST)	Human	E. coli
	IL-18 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with GST tag. The predicted molecular weight is 48.6 kDa and the accession number is Q14116.
TMPJ-00344	IL-18RAP Protein, Human, Recombinant (hFc & His)	Human	HEK293 Cells
	IL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 a...
TMPJ-00074	IL-18BP Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Interleukin-18-binding protein, also known as Tadekinig-alfa and IL18BP, contains 1 Ig-like C2-type domain. IL18BP is constitutively expressed and secreted in mononuclear cells. IL18BP functions as an IL18 inhibitor. IL1...
TMPY-06578	IL-18R alpha Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293 Cells
	IL-18R alpha Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 64.30 kDa and the accession number is NP_003846.1.
TMPY-06897	IL-18R alpha Protein, Human, Recombinant (His), Biotinylated	Human	HEK293 Cells
	IL-18R alpha Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.21 kDa and the accession number is NP_003846.1.
TMPJ-00070	IL-18 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Interleukin-18 is a secreted protein and it belongs to the IL-1 family. IL-18 is a proinflammatory cytokine and produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The c...
TMPY-00844	IL-17RD Protein, Human, Recombinant (His)	Human	HEK293 Cells
	IL-17RD Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.5 kDa and the accession number is Q8NFM7-1.
TMPK-00076	IL-18 Protein (Primary Amine Labeling), Human, Recombinant, Biotinylated	Human	E. coli
	Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop...
TMPJ-01056	IL-18 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Interleukin-18 (IL-18）is a protein which belongs to the IL-1 family. It is expressed as a 24 kDa precursor by endothelial and epithelial cells, keratinocytes, gamma δ T cells, and phagocytes. Mature mouse IL-18 shares 63...
TMPY-00609	IL-18R beta/IL-18RAP Protein, Mouse, Recombinant (His)	Mouse	Baculovirus Insect Cells
	IL-18R beta/IL-18RAP Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 40.1 kDa and the accession number is Q0VBK3.
TMPK-00661	IL-22 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function, including regulation of epithelial cell growth and permeab...
TMPY-06312	IL-18R beta/IL-18RAP Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	IL-18R beta/IL-18RAP Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 41.76 kDa and the accession number is NP_003844.1.
TMPY-06316	IL-18R beta/IL-18RAP Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293 Cells
	IL-18R beta/IL-18RAP Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 67.04 kDa and the accession number is NP_003844.1.
TMPY-01200	IL-18R beta/IL-18RAP Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	IL-18R beta/IL-18RAP Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.2 kDa and the accession number is O95256-1.
TMPK-01194	IL-22 Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	E. coli
	The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function, including regulation of epithelial cell growth and permeab...
TMPK-00317	IL-18R alpha Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced I...
TMPK-00512	IL-18R alpha Protein, Cynomolgus, Recombinant (aa 22-329, His)	Cynomolgus	HEK293 Cells
	Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced I...
TMPK-00316	IL-18R alpha Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced I...
TMPK-00082	IL-18BP Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggestin...
TMPK-00515	IL-1 beta/IL-1F2 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	E. coli
	Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation. IL-1...
TMPY-02597	IL-37 Protein, Human, Recombinant	Human	E. coli
	Interleukin 1 family member 7, or interleukin 37 (IL1F7 / IL37 / IL-1H4) is a secretory protein belonging to the Interleukin 1 family. IL-1F7 was localized in human peripheral monocytic cells. It has been localized the e...
TMPK-00162	IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	E. coli
	Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation. IL-1...
TMPK-00161	IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi)	Human	E. coli
	Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation. IL-1...
TMPJ-00789	Flagellin Protein, Salmonella Typhimurium, Recombinant	Salmonella typhimurium	E. coli
	Flagellin is the major structural protein monomer of bacterial flagella. Flagellin through binding to its receptor and activation of antigen presenting cells stimulates the innate and adaptive immune responses. Flagellin...